Related Experiment Video
Updated: Sep 28, 2025

Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
Nanoparticle delivery systems for substance use disorder
Vishal Kasina1, Robert J Mownn1, Raman Bahal1
1Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, 06269, USA.
Nanotechnology offers new ways to deliver therapies across the brain for substance use disorder (SUD). This review explores nanocarrier systems for improved brain drug delivery and future SUD treatments.
Area of Science:
- Biomedical Engineering
- Neuroscience
- Pharmacology
Background:
- Nanotechnology innovations are crucial for healthcare, particularly for brain diseases requiring advanced therapeutic delivery.
- Nanoparticle systems can transport diagnostic and therapeutic agents across biological barriers to targeted cells over time.
- Substance Use Disorder (SUD) has many identified therapeutic targets, but clinical translation is limited by challenges in brain-specific drug delivery.
Purpose of the Study:
- To review nanotherapeutic brain delivery systems for Substance Use Disorder (SUD).
- To evaluate potential approaches and limitations of nanocarrier-based treatments for SUD.
- To highlight promising strategies and future directions in nanomedicine for SUD.
Main Methods:
- Literature review of nanotechnology applications in brain disease treatment.
- Analysis of nanocarrier capabilities for crossing biological barriers.
- Evaluation of preclinical and clinical studies on nanotherapeutics for SUD.
Main Results:
- Nanoparticle delivery systems show potential for targeted drug delivery to the brain.
- Significant challenges remain in translating nanotherapeutic strategies for SUD into clinical practice.
- Various nanocarrier strategies show promise for future SUD treatment development.
Conclusions:
- Nanotechnology holds significant promise for overcoming brain delivery challenges in SUD.
- Further research and development are needed to optimize nanocarrier systems for effective SUD therapies.
- Nanomedicine offers a promising avenue for advancing treatments for brain diseases like SUD.
More Related Videos
10:16Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier
Published on: February 8, 2017
09:16A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
Published on: January 22, 2016
Related Concept Videos
Drug Abuse and Addiction: Pharmacological Phenomena
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Drug Delivery: Overview
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Drug Dependence
Factors Affecting Dissolution: Particle Size and Effective Surface Area