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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Preventive Healthcare Services01:30

Preventive Healthcare Services

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Cancer Vaccines01:30

Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Tumor Progression02:07

Tumor Progression

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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Progress in prostate cancer prevention.

Gabriele Cozzi1, Gennaro Musi1,2, Matteo Ferro1

  • 1Division of Urology, European Institute of Oncology, IRCCS.

European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)
|March 30, 2022
PubMed
Summary
This summary is machine-generated.

Prostate cancer prevention is challenging due to unknown causes. New diagnostic biomarkers, imaging tools, and targeted biopsies offer improved early detection and care for this common cancer.

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Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking
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Area of Science:

  • Oncology
  • Urology
  • Genetics

Background:

  • Prostate cancer is the second most diagnosed cancer globally and fourth in mortality.
  • Etiology and risk factors remain largely unknown, complicating primary prevention strategies.
  • Current screening methods, like the prostate-specific antigen (PSA) test, are insufficient for improving early detection and patient outcomes.

Purpose of the Study:

  • To discuss emerging diagnostic biomarkers for prostate cancer.
  • To explore advancements in imaging tools for prostate cancer detection.
  • To highlight the potential of targeted prostate biopsies in improving diagnosis and care.

Main Methods:

  • Review of current literature on prostate cancer diagnostics.
  • Discussion of novel biomarkers and imaging technologies.
  • Analysis of targeted biopsy techniques.

Main Results:

  • Novel biomarkers and advanced imaging show promise for earlier and more accurate prostate cancer detection.
  • Targeted prostate biopsies may improve diagnostic yield compared to standard methods.
  • Hereditary factors, including germline mutations, play a role in approximately 10% of prostate cancer cases.

Conclusions:

  • Improved diagnostic tools are crucial for enhancing prostate cancer prevention and care.
  • Future strategies should integrate novel biomarkers, advanced imaging, and targeted biopsies.
  • Further research is needed to fully elucidate prostate cancer etiology and optimize early detection.