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Published on: June 2, 2014
Dialysis headache: characteristics, impact and cerebrovascular evaluation
Eduardo Sousa Melo1, Rodrigo Pinto Pedrosa2, Filipe Carrilho Aguiar3
1Universidade Federal de Pernambuco, Programa de Pós-Graduação em Neuropsiquiatria e Ciências do Comportamento, Recife PE, Brazil.
Insights
Dialysis headache is common and impacts patient quality of life. This study identified factors like female sex and longer dialysis duration associated with its occurrence.
Area of Science:
- Nephrology
- Neurology
- Clinical Research
Background:
- Headache is a frequent symptom during hemodialysis sessions.
- Dialysis headache, despite its prevalence, remains understudied.
Purpose of the Study:
- To evaluate the characteristics and impact of dialysis headache.
- To identify factors associated with dialysis headache.
- To compare cerebral vasculature behavior in patients with and without dialysis headache.
Main Methods:
- Cross-sectional study of 100 hemodialysis patients.
- Assessment using questionnaires (HIT-6, HADS, SF-36) and Transcranial Doppler ultrasonography.
- Analysis of demographic, clinical, and vascular parameters.
Main Results:
- 49% of patients experienced dialysis headache.
- Factors associated with dialysis headache include female sex, younger age, higher education, and longer dialysis duration.
- Patients with dialysis headache reported worse quality of life and altered cerebral blood flow patterns (lower pulsatility index).
Conclusions:
- Dialysis headache is a common complication of hemodialysis.
- It significantly impacts patient quality of life and is linked to cerebral vasodilatation patterns.
- Further research is needed to understand and manage dialysis headache.
Background:
Headache is one of the most frequent symptoms that occur during hemodialysis sessions. Despite the high prevalence of dialysis headache, it has been little studied.
Objective:
To evaluate the characteristics, impact and factors associated with dialysis headache. The behavior of the cerebral vasculature was also compared between patients with and without dialysis headache.
Methods:
This was a cross-sectional study. Consecutive patients who underwent hemodialysis were assessed through a semi-structured questionnaire, the Headache Impact Test (HIT-6), the Hospital Anxiety and Depression Scale and the Short Form-36 Health Survey (SF-36). Transcranial Doppler ultrasonography was performed in the first and fourth hours of hemodialysis.
Results:
A total of 100 patients were included; 49 of them had dialysis headache. Women (OR=5.04; 95%CI 1.95-13.04), younger individuals (OR=1.05; 95%CI 1.01-1.08), individuals with higher schooling levels (OR=3.86; 95%CI 1.4-10.7) and individuals who had spent longer times on dialysis programs (OR=0.99; 95%CI 0.98-1) had more dialysis headache (logistic regression). Individuals with dialysis headache had worse quality of life in the domains of pain and general state of health (56.9 versus 76.4, p=0.01; 49.7 versus 60.2, p=0.03, respectively). Dialysis headache was associated with significantly greater impact on life (OR=24.4; 95%CI 2.6-226.6; logistic regression). The pulsatility index (transcranial Doppler ultrasonography) was lower among patients with dialysis headache than among those without them.
Conclusions:
Dialysis headaches occur frequently and are associated with worse quality of life and patterns of cerebral vasodilatation.
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