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Managing Pain and Discomfort in Children with Cancer
Clinton Fuller1, Henry Huang2, Rachel Thienprayoon3
1Department of Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital, Baylor College of Medicine, 6621 Fannin St, Ste A3300, Houston, TX, USA. clfuller@bcm.edu.
Insights
Managing cancer pain in children requires a comprehensive approach. This review highlights pharmacology, interventional techniques, and complementary therapies for effective pediatric cancer pain management.
Area of Science:
- Pediatric Oncology
- Pain Management
- Palliative Care
Background:
- Approximately 15,600 children are diagnosed with cancer each year.
- Many experience cancer-related pain, which can be intractable due to disease progression or treatment side effects.
- Effective pain management is crucial for improving quality of life in pediatric cancer patients.
Purpose of the Study:
- To critically evaluate current literature on pain management strategies for children with cancer.
- To emphasize up-to-date findings in pharmacological, interventional, and complementary/alternative medicine approaches.
- To provide a comprehensive overview for clinicians managing pediatric cancer pain.
Main Methods:
- Literature review focusing on pharmacology, interventional pain management, and complementary and alternative medicine.
- Critical evaluation of existing research and clinical findings.
- Synthesis of evidence to support a multifaceted pain management plan.
Main Results:
- Pharmacological interventions, alternative medications, and routes of administration are key components.
- Complementary and alternative medicine (CAM) techniques offer additional therapeutic options.
- Interventional pain procedures can be utilized when other methods are insufficient.
- High-level evidence is often limited for some advanced techniques.
Conclusions:
- A multifaceted approach is recommended for pediatric cancer pain management, integrating the biopsychosocial model.
- Evidence-based pharmacology should be the foundation of treatment.
- Complementary and alternative medicine and interventional procedures should be incorporated as needed.
- Further research is needed to strengthen the evidence base for various interventions.
Purpose Of Review:
Approximately 15,600 children are diagnosed with cancer annually. Many of these children have cancer-related pain that improves with cancer treatment, but some develop intractable pain from cancer progression or sequelae from treatment modalities. The purpose of this paper is to provide a critical evaluation of the literature relevant to pain management in children with cancer. We intend to emphasize important and up-to-date findings in pharmacology, interventional pain management, and complementary and alternative medicine.
Recent Findings:
Alternative medications and routes of administration, complementary and alternative medicine techniques, and interventional pain procedures offer possible routes for a multi-pronged pediatric cancer pain management plan, although high-level data is often lacking. To improve pediatric cancer pain management, a multifaceted approach embracing the biopsychosocial model of pain is recommended, incorporating evidence-based pharmacology, complementary and alternative medicine techniques, and if needed, interventional pain procedures.
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