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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
180

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Related Experiment Video

Updated: Sep 28, 2025

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
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Radioembolization, Principles and indications.

Hojjat Ahmadzadehfar1, Harun Ilhan2,3, Marnix G E H Lam4

  • 1Nuclear Medicine, Klinikum Westfalen GmbH, Dortmund, Germany.

Nuklearmedizin. Nuclear Medicine
|March 30, 2022
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Summary
This summary is machine-generated.

Radioembolization uses radionuclide microspheres to treat liver tumors. This review covers therapy planning, dosimetry, and indications for 90Y-glass, resin microspheres, and 166Ho-microspheres.

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Area of Science:

  • Interventional oncology
  • Nuclear medicine
  • Radiotherapy

Background:

  • Radioembolization is a targeted liver cancer therapy using radioactive microspheres.
  • It involves delivering radionuclides directly to liver tumors via hepatic arteries.
  • This minimally invasive procedure offers a localized treatment approach.

Purpose of the Study:

  • To review therapeutic planning and dosimetry for radioembolization.
  • To outline the primary indications for using specific microsphere types.
  • To provide an overview of 90Y-glass, 90Y-resin, and 166Ho-microsphere applications.

Main Methods:

  • Literature review focusing on radioembolization techniques.
  • Analysis of dosimetry and treatment planning strategies.
  • Compilation of clinical data on microsphere indications.

Main Results:

  • Detailed discussion of therapy planning and dosimetry considerations.
  • Summary of established indications for 90Y-glass and 90Y-resin microspheres.
  • Overview of 166Ho-microsphere use in liver tumor treatment.

Conclusions:

  • Effective radioembolization requires precise therapy planning and dosimetry.
  • Specific microsphere types (90Y, 166Ho) have distinct indications in liver cancer.
  • This review consolidates key aspects for clinical application.