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Updated: Sep 28, 2025
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
[65 years old man of chronic inflammatory demyelinating polyneuritis (CIDP) which presented radicular swelling and
Toshiyuki Tezuka1, Yusuke Kaneko1, Syota Yamada1
1Department of Neurology, Niigata Prefectural Central Hospital.
Abstract:
The case is a 65 years old man. He noticed muscle weakness of lower limbs from 3 years ago. Dysesthesia was developed, He came in our hospital in X year. He was detected muscle weakness, sensory disturbance in distal lower limbs predominance and detected radicular significant swelling in spinal cord MRI and diagnosed it with chronic inflammatory demyelinating polyneuritis (CIDP). In the follow-up purpose of other diseases regularly, it was confirmed that nerve root was gradually swelling from around 7 years before the onset. The radicular swelling is one of the characteristics in CIDP, supports the diagnosis. This case was the valuable case that was able to chase image progress before the onset.
Insights
This case study highlights a 65-year-old man diagnosed with chronic inflammatory demyelinating polyneuritis (CIDP). It demonstrates characteristic nerve root swelling on MRI, observed years before symptom onset, supporting early diagnosis.
Area of Science:
- Neurology
- Radiology
- Immunology
Background:
- Chronic inflammatory demyelinating polyneuritis (CIDP) is a rare autoimmune disorder affecting peripheral nerves.
- Early diagnosis and understanding of disease progression are crucial for effective management.
Purpose of the Study:
- To present a unique case of CIDP with documented, progressive nerve root swelling preceding clinical onset.
- To illustrate the diagnostic value of serial spinal cord MRI in identifying characteristic CIDP features.
Main Methods:
- A 65-year-old male patient presented with progressive lower limb muscle weakness and dysesthesia.
- Spinal cord magnetic resonance imaging (MRI) revealed significant radicular swelling.
- Diagnosis of CIDP was established based on clinical presentation and imaging findings.
Main Results:
- The patient exhibited muscle weakness and sensory disturbances predominantly in the distal lower limbs.
- Serial MRI demonstrated gradual nerve root swelling over several years, preceding the onset of symptoms by approximately 7 years.
- This radicular swelling was identified as a key characteristic supporting the CIDP diagnosis.
Conclusions:
- This case underscores the significance of nerve root swelling as a characteristic imaging finding in CIDP.
- The ability to track the imaging progression of radicular swelling before symptom onset offers valuable insights into the early stages of CIDP.
