Long-Term Outcomes in Patients with Not-Retrieval Inferior Vena Cava Filter Under Anticoagulation

Ryohei Sakai1, Shinya Fujiki1, Takeshi Kashimura1

  • 1Department of Cardiovascular Medicine, Niigata University Graduate School of Medical and Dental Sciences.

Insights

Retrieving inferior vena cava (IVC) filters is recommended, but many remain. Long-term anticoagulation in patients with non-retrieved IVC filters can prevent deep vein thrombosis (DVT) recurrence, despite bleeding risks.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiology

Background:

  • Permanent inferior vena cava (IVC) filters are associated with increased deep vein thrombosis (DVT) risk.
  • Guidelines recommend IVC filter retrieval, yet retrieval rates remain low in clinical practice.
  • The long-term outcomes of patients with non-retrieved IVC filters on anticoagulation are not well-established.

Purpose of the Study:

  • To investigate the long-term prognosis of patients with non-retrieved IVC filters.
  • To evaluate the incidence of venous thromboembolism (VTE) recurrence and bleeding events in this cohort.
  • To assess the effectiveness and safety of continued anticoagulation therapy in patients with non-retrieved IVC filters.

Main Methods:

  • Retrospective study of 195 patients who underwent IVC filter implantation between 2006 and 2017.
  • Analysis of patient data from three institutions in Niigata City.
  • Inclusion of data on deaths, VTE recurrence, bleeding events, and anticoagulation status during a mean 5.0-year follow-up.

Main Results:

  • A total of 158 patients (81%) had non-retrieved IVC filters, with a retrieval rate of 19.0%.
  • The non-retrieved group was older and had a higher prevalence of cancer.
  • During follow-up, 6 symptomatic DVT events and 13 bleeding events occurred. Cancer was the only significant prognostic risk factor for mortality.

Conclusions:

  • Despite low retrieval rates, appropriate anticoagulation in patients with non-retrieved IVC filters appears effective in preventing DVT recurrence.
  • Long-term anticoagulation may increase bleeding risk, but benefits in preventing VTE recurrence are evident.
  • Continued anticoagulation is a viable strategy for managing patients with non-retrieved IVC filters.

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