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Survivorship Analysis in Asymptomatic COVID-19+ Hip Fracture Patients: Is There an Increase in Mortality?
Mason D Vialonga1, Luke G Menken1, Alex Tang1
1Division of Orthopaedic Trauma and Adult Reconstruction, Department of Orthopaedic Surgery, Jersey City Medical Center - RWJBarnabas Health, Jersey City, NJ, USA.
Insights
Asymptomatic hip fracture patients with COVID-19 had higher mortality rates at 30 and 90 days compared to those without the virus. COVID-19 positivity independently increased mortality risk in these patients.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Epidemiology
Background:
- Hip fracture surgery outcomes are well-documented.
- The impact of concurrent COVID-19 infection on hip fracture patients is less understood.
- Asymptomatic COVID-19 infection presents a unique challenge in surgical patient management.
Purpose of the Study:
- To compare 30-day and 90-day mortality rates in asymptomatic hip fracture patients with and without COVID-19.
- To identify if COVID-19 status independently affects mortality in this patient cohort.
Main Methods:
- Retrospective review of 149 consecutive hip fracture patients during the COVID-19 pandemic.
- Comparison of mortality between asymptomatic COVID-19 positive and negative patient groups.
- Primary outcomes: 30-day and 90-day mortality; secondary outcomes: length of stay, comorbidities.
Main Results:
- COVID-19 positive patients exhibited significantly higher 30-day (26.7% vs 6.0%) and 90-day (41.7% vs 17.2%) mortality.
- COVID-19 positive patients had a higher prevalence of pre-existing respiratory disease (46.7% vs 11.2%).
- Cox regression indicated COVID-19 positivity as an independent risk factor for mortality, not pre-existing respiratory disease.
Conclusions:
- COVID-19 positivity is an independent risk factor for increased mortality in asymptomatic hip fracture patients.
- Optimized care protocols, including prompt orthogeriatric assessment and efficient operating room utilization, are crucial.
- Managing COVID-19 in hip fracture patients requires specific considerations to maintain standards of care.
Purpose:
Mortality rates following hip fracture surgery have been well-studied. This study was conducted to examine mortality rates in asymptomatic patients presenting for treatment of acute hip fractures with concurrent positive COVID-19(+) tests compared to those with negative COVID-19(-) tests.
Materials And Methods:
A total of 149 consecutive patients undergoing hip fracture surgery during the COVID-19 pandemic at two academic medical centers were reviewed retrospectively. Patients were divided into two groups for comparative analysis: one group included asymptomatic patients with COVID-19+ tests versus COVID-19- tests. The primary outcome was mortality at 30-days and 90-days.
Results:
COVID-19+ patients had a higher mortality rate than COVID-19- patients at 30-days (26.7% vs 6.0%, P=0.005) and 90-days (41.7% vs 17.2%, P=0.046) and trended towards an increased length of hospital stay (10.1±6.2 vs 6.8±3.8 days, P=0.06). COVID-19+ patients had more pre-existing respiratory disease (46.7% vs 11.2%, P=0.0002). Results of a Cox regression analysis showed an increased risk of mortality at 30-days and 90-days from COVID-19+ status alone without an increased risk of death in patients with pre-existing chronic respiratory disease.
Conclusion:
Factors including time to surgery, age, preexisting comorbidities, and postoperative ambulatory status have been proven to affect mortality and complications in hip fracture patients; however, a positive COVID-19 test result adds another variable to this process. Implementation of protocols that will promote prompt orthogeriatric assessments, expedite patient transfer, limit operating room traffic, and optimize anesthesia time can preserve the standard of care in this unique patient population.
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