Panama: An Open-Source Educational App for Ion Channel Biophysics Simulation

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Modeling Biological Membranes with Circuit Boards and Measuring Electrical Signals in Axons: Student Laboratory Exercises
13:56

Modeling Biological Membranes with Circuit Boards and Measuring Electrical Signals in Axons: Student Laboratory Exercises

Published on: January 18, 2011

Binita Rajbanshi1, Anuj Guruacharya2

  • 1Department of Epileptology, University Hospital Bonn, Bonn, Germany.

Frontiers in Neuroinformatics
|March 31, 2022
PubMed

Keywords:
Hodgkin–Huxley simulationbiophysicseducational purposesion channelsweb app for neuroscience

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Ion channels are specialized integral membrane proteins on the plasma membrane that allow specific...
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Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
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Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
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Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
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