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Global status and trends in heart failure with preserved ejection fraction over the period 2009-2020: A bibliometric
Qiuju Dong1, Junwei Zhang, Qinghua Han
1Hospital of Integrated Traditional and Western Medicine, Shanxi University of Chinese Medicine, Taiyuan, Shanxi, China,Third Clinical College, Shanxi University of Chinese Medicine, Taiyuan, Shanxi, China,The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Jinzhong, Shanxi, China,School of Management, Shanxi Medical University, Jinzhong, Shanxi, China,School of Computer and Information Technology, Shanxi University, Taiyuan, Shanxi, China,First Hospital, Shanxi Medical University, Taiyuan, Shanxi, China.
Insights
This bibliometric analysis of heart failure with preserved ejection fraction (HFpEF) research from 2009-2020 reveals increasing global output. Key research areas include diagnosis, outcomes, and diastolic dysfunction, with emerging trends in inflammation and phenotype.
Area of Science:
- Cardiology
- Bibliometrics
- Medical Research
Background:
- Heart failure with preserved ejection fraction (HFpEF) accounts for 50% of heart failure cases.
- Currently, no effective treatment strategies exist for HFpEF.
- This study analyzes scientific literature on HFpEF from 2009-2020.
Purpose of the Study:
- To evaluate global scientific output in HFpEF research.
- To explore the current research status and emerging trends in HFpEF.
- To provide guidance for researchers in the HFpEF field.
Main Methods:
- Bibliometric analysis of 1971 documents (articles and reviews) published between 2009-2020.
- Data retrieved from Science Citation Index Expanded (SCIE) in Web of Science.
- Analysis conducted using bibliometrix R-package, VOSviewer, and CiteSpace.
Main Results:
- Annual document output increased from 24 to 353.
- USA led in publications, with Mayo Clinic as a leading institution.
- Key terms: mortality, dysfunction, diagnosis, outcomes, diastolic dysfunction; Emerging trends: hemodynamics, comorbidity, inflammation, phenotype.
Conclusions:
- Bibliometric analysis provides a comprehensive overview of HFpEF research productivity.
- Identifies research hotspots, frontiers, and potential collaborators.
- Offers valuable guidance for future in-depth HFpEF research.
Background:
Heart failure with preserved ejection fraction (HFpEF) comprises about 50% of the cases of heart failure (HF), but so far there is no effective treatment strategy. This study used bibliometric methods to analyze the scientific literature on HFpEF in 2009 to 2020, and evaluate the global scientific output of HFpEF research, in order to explore the research status and trends in this field.
Methods:
Documents about the HFpEF research published in 2009 to 2020 were retrieved from Science Citation Index Expanded (SCIE) in Web of Science. This study used bibliometrix R-package, VOSviewer, and CiteSpace to conduct the bibliometric analysis.
Results:
A total of 1971 documents (1508 articles and 283 reviews) were retrieved to construct the local HFpEF literature collection for analysis. The number of annual documents had increased year by year in general, from 24 to 353. Relevant documents were mainly written in English, and mostly focused on the field of "Cardiovascular System Cardiology." USA ranked first in the relevant countries/regions with most documents, and the leading affiliation was Mayo Clin. Shah SJ was the most productive author, while Borlaug BA ranked highest among the local cited authors and G-index. Circulation was the most local cited source, while Eur J Heart Fail published the most documents and was rated as the top source in terms of G-index. "Paulus WJ, 2013, J Am Coll Cardiol" was the top local cited document within the local HFpEF literature collection, while "Owan TE, 2006, New Engl J Med" outside the local HFpEF literature collection was the most local cited reference. The keywords such as "mortality," "dysfunction," "diagnosis," "outcomes," and "diastolic dysfunction" were most frequent, while "hemodynamics," "comorbidity," "myocardial infarction," "inflammation," and "phenotype" indicated research frontiers or emerging trends. Furthermore, this study also found some deeper bibliometric relationships through bibliographic networks.
Conclusions:
Due to the multi-dimensional bibliometric analysis, this study shows a wide view of scientific productivity related to HFpEF, and provides valuable guidance for researchers interested in HFpEF, assisting them in understanding the research status, identifying potential collaborators, discovering research hotspots and frontiers, and conducting more in-depth research.
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