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Published on: December 18, 2016
Focal Epilepsy in Individuals with Laron Syndrome
Lotem Goldberg1,2, Zvi Laron3,4, Liora Kornreich3,5
1Department of Pediatrics B, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel, lotem.yahav@gmail.com.
Objective:
The aim of the study was to describe focal epilepsy in patients with Laron syndrome (LS).
Methods:
Data were retrieved from medical records of a single-center cohort of 75 patients with LS.
Results:
We describe for the first time 4 patients with concomitant focal epilepsy and LS. Two of them experienced episodes of status epilepticus. Electroencephalogram examination in all 4 patients showed interictal epileptiform discharges in the temporal regions. Three achieved long-term seizure freedom on antiseizure medications.
Conclusion:
Patients with LS may be at risk of developing focal epilepsy, which seems to be unrelated to hypoglycemic episodes in childhood.
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