An epidemiological study and trend analysis of laboratory confirmed COVID-19 cases among children in North India
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Updated: Sep 28, 2025

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
Published on: September 7, 2022
Sabba Mussadiq1, Rajesh K Verma1, Dharmendra P Singh1
1Department of Microbiology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India.
Insights
Children can contract and transmit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19). Most pediatric COVID-19 cases were asymptomatic, highlighting children
Area of Science:
- Pediatric Infectious Diseases
- Epidemiology
- Public Health
Background:
- The transmission dynamics and clinical impact of SARS-CoV-2 in children remain incompletely understood.
- Ascertaining the role of pediatric populations in COVID-19 transmission is crucial for public health strategies.
Purpose of the Study:
- To investigate the epidemiological trends and clinical features of COVID-19 infections in children.
- To describe month-wise incidence and characteristics of pediatric SARS-CoV-2 cases.
Main Methods:
- A cross-sectional study analyzed pediatric samples tested for SARS-CoV-2 via real-time RT-PCR.
- Data were collected from June to November 2020, encompassing suspected cases from various districts.
Main Results:
- Out of 62,030 pediatric samples, 1.3% (847) tested positive for SARS-CoV-2.
- The majority of positive cases were in the 11-15 age group, with a median age of 14 years.
- Approximately 62.1% of infected children were asymptomatic, and cases peaked in September 2020.
Conclusions:
- Children are susceptible to SARS-CoV-2, though they represent a small fraction of confirmed cases.
- Asymptomatic pediatric infections suggest a potential role in community transmission.
- Targeting pediatric immunization is vital for controlling the evolving COVID-19 pandemic.
Background:
The role of children in transmitting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is difficult to ascertain and the consequences remain unclear. This is necessary for public health or infection control purposes. The objective of this study was to describe the epidemiological, month-wise trends and clinical characteristics of coronavirus disease 2019 (COVID-19) infection among children in a tertiary care hospital.
Materials And Methods:
A cross-sectional study was performed on all pediatric samples of suspected cases of SARS-CoV-2 infection. The samples were received from the adjoining districts and our Institution in the Department of Microbiology from June to November 2020. Cases were then confirmed by real-time reverse transcriptase-polymerase chain reaction.
Results:
Of the total 62,030 pediatric samples tested, 847 (1.3%) were SARS-CoV-2 positive. The majority of positive cases were between the ages of 11-15 years. The median age of confirmed patients was 14 years. The male to female ratio was 1.5:1. Infants represented 1.6% of the positive cases. About 62.1% of all positive cases were asymptomatic. Childhood cases increased from June 2020 and peaked in September 2020 before declining.
Conclusion:
Children of all ages appeared susceptible to COVID-19 and accounted for a very small proportion of confirmed cases. Mostly, children were found to be asymptomatic. Young children can be important transmitters of SARS-CoV-2 infection in the general population. This population can be important for targeting immunization efforts throughout a rapidly evolving situation. Our findings provide further evidence of the distribution of infection in children and the transmission of SARS-CoV-2.
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