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Updated: Sep 28, 2025

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
Underactive urinary bladder - Masquerading as abdominal ascites
Raghubir Bhardwaj1, Harish K Sinha1
1Department of Urology, Tata Main Hospital, Jamshedpur, Jharkhand, India.
Aging can impair bladder emptying, causing urinary retention and affecting quality of life. Effective treatments for underactive detrusor are lacking, highlighting a need for further research into this common condition.
Area of Science:
- Gerontology
- Urology
- Physiology
Background:
- Impaired urinary bladder evacuation is common with aging, affecting both men and women.
- Symptoms include storage, voiding, and post-micturition issues, potentially leading to urinary retention and reduced quality of life.
- The exact causes of underactive detrusor are not fully understood, and diagnostic criteria are not standardized.
Observation:
- Urodynamic study (UDS) is the current standard for diagnosing underactive detrusor, despite being invasive.
- A 73-year-old male presented with urinary symptoms and abdominal distension, indicative of bladder dysfunction.
- The case highlights the clinical challenges associated with diagnosing and managing impaired bladder emptying.
Findings:
- Underactive detrusor, a condition affecting bladder emptying, lacks effective therapeutic options.
- Current treatment goals focus on symptom improvement and complication risk reduction.
- Further investigation is needed to understand the etiopathogenesis and develop better treatments.
Implications:
- This condition significantly impacts patients' quality of life, necessitating improved diagnostic and therapeutic strategies.
- The lack of effective treatments underscores the need for advancements in urological care for the aging population.
- Developing non-invasive diagnostic methods and effective therapies for underactive detrusor is a critical unmet need.
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