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Regulation of Metabolism01:19

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Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
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Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
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Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Editorial: Metabolism and Epigenetics

Carlos Sebastian1,2, Joaquim S L Vong3, Manasi K Mayekar4

  • 1Department of Cell Biology, Physiology and Immunology, School of Biology, University of Barcelona, Barcelona, Spain.

Frontiers in Genetics
|April 1, 2022
PubMed
Summary

No abstract available in PubMed .

Keywords:
DNAchromatindevelopmentdiseasehistonemetabolites

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