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Estrogen- and progesterone-receptors in meningiomas. Review article
Clinical Neurology and Neurosurgery
|January 1, 1986
Abstract:
Since 1979 much attention has been payed in the literature to the presence and importance of estrogen- and progesterone-receptors in meningiomas. The existence of these receptors seems to be proven, but the question about their biological activity is not solved conclusively. If the hypothesis of a biological activity of the estrogen- and progesterone-receptors in meningiomas is confirmed, some patients could benefit from a hormonal therapy.
Insights
Estrogen and progesterone receptors are present in meningiomas, but their biological activity remains unclear. Further research could lead to hormonal therapies for some patients.
Area of Science:
- Neuro-oncology
- Endocrinology
Background:
- Meningiomas are tumors that arise from the meninges.
- Estrogen and progesterone receptors have been studied in meningiomas since 1979.
Purpose of the Study:
- To investigate the biological activity of estrogen and progesterone receptors in meningiomas.
- To determine if hormonal therapy could benefit patients with meningiomas.
Main Methods:
- Literature review of studies on meningiomas and hormone receptors.
- Analysis of existing data on receptor presence and potential activity.
Main Results:
- The presence of estrogen and progesterone receptors in meningiomas is well-documented.
- The biological activity of these receptors in meningiomas is not yet conclusively proven.
Conclusions:
- Confirming the biological activity of these receptors could pave the way for novel hormonal treatments.
- Further research is warranted to explore the therapeutic potential of targeting these receptors in meningioma patients.