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Calcitonin and reflex sympathetic dystrophy syndrome
Clinical Rheumatology
|September 1, 1986
Summary
Salmon calcitonin combined with physical therapy significantly improved pain in patients with reflex sympathetic dystrophy syndrome within one week. Calcitonin may be effective even when physical therapy is not feasible.
Area of Science:
- Pain Management
- Endocrinology
- Physical Medicine
Background:
- Reflex sympathetic dystrophy syndrome (RSD) presents treatment challenges.
- Assessing the efficacy of various RSD treatment modalities is difficult.
- Comparative studies on RSD treatments are lacking.
Purpose of the Study:
- To investigate the efficacy of physical therapy with or without salmon calcitonin for RSD.
- To compare outcomes between physical therapy alone and combined therapy.
Main Methods:
- 24 RSD patients were randomly assigned to two groups.
- Group I received physical therapy (pressure, electrotherapy, exercise).
- Group II received physical therapy plus 100 MRC units of salmon calcitonin daily for 3 weeks.
Main Results:
- Significant pain reduction was observed in Group II within one week.
- Efficacy was assessed using clinical, biochemical, and scintigraphic parameters.
- Patient's ability to resume work was also evaluated.
Conclusions:
- Calcitonin, in addition to physical therapy, is recommended for RSD treatment.
- Calcitonin monotherapy may be an option if physical therapy is not possible.