Related Experiment Video
Updated: Sep 28, 2025
06:36
Nerve Stimulator-guided Injection of Autologous Stem Cells Near the Equine Left Recurrent Laryngeal Nerve
Published on: September 26, 2018
9.1K
Laryngeal Embryonal Rhabdomyosarcoma: A rare adult neoplasm
Farah Hafiz Yusuf1, Irfan Shaikh1, Muntazir Hussain2
1Department of Otolaryngology, Dow Medical College, Karachi, Pakistan.
Ear, Nose, & Throat Journal
|April 1, 2022
Summary
Embryonal rhabdomyosarcoma, typically a pediatric cancer, rarely affects adults. This case highlights a 63-year-old man diagnosed with this rare laryngeal cancer.
Area of Science:
- Oncology
- Pathology
Background:
- Embryonal rhabdomyosarcoma is the most common pediatric soft tissue sarcoma.
- This subtype is exceptionally rare in adult patients, particularly in the head and neck region.
Observation:
- A 63-year-old male presented with progressive hoarseness, difficulty swallowing solids, and shortness of breath.
- Clinical examination and subsequent investigations revealed a laryngeal mass.
Findings:
- The laryngeal mass was diagnosed as embryonal rhabdomyosarcoma.
- This represents an extremely rare occurrence of this specific cancer subtype in an adult larynx.
Implications:
- This case underscores the importance of considering rare diagnoses in adult head and neck cancers.
- Highlights the need for further research into adult embryonal rhabdomyosarcoma presentation and management.
Related Concept Videos
01:03Rous Sarcoma Virus (RSV) and Cancer
5.5K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
5.5K
01:21Larynx
2.3K
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
2.3K
01:20The Retinoblastoma Gene
4.2K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.2K
01:21Barrett Esophagus-II: Clinical Manifestations and Management
331
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
331
02:23Abnormal Proliferation
4.7K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.7K