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Updated: Sep 28, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
Analysis of contrast-enhanced spectral chest CT optimal monochromatic imaging combined with ASIR and ASIR-V
1Department of Ultrasound, Jinan Maternity and Child Care Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, P.R. China. 289954749@qq.com.
Objective:
The aim of the study was to explore the application of spectral chest CT optimal monochromatic imaging combined with ASIR and ASIR-V to optimize the image quality in the arterial phase.
Patients And Methods:
62 patients who had undergone contrast-enhanced chest CT examination using spectral CT were included. Twelve sets of arterial phase images were acquired using GSI mode. The CNR, BHA values and subjective scores were statistically analysed. Thus, optimal monochromatic images were obtained. Then, the images were acquired by reconstruction using ASIR and ASIR-V at 30%, 50% and 70% levels. Six sets of images were obtained and compared with QC and the monochromatic image under FBP mode.
Results:
In FBP mode, the CNR of 80-keV images was 7.7±2.0, showing no significant difference with QC images (p > 0.05). The BHA value in the blood vessels was 45.2±23.1, which was lower than that in QC images (p < 0.05). The subjective image quality score of 80-keV images was 4.50±0.62. No significant difference was found in QC images (p > 0.05). The subjective score of the artefacts was 2.45±0.62, which was lower than that of QC images (p < 0.05). Thus, 80 keV was chosen as the optimal monochromatic energy to be reconstructed with ASIR and ASIR-V. The CNR of the 80keV+50% ASIR-V group was 13.9±4.3, which was higher than those of 140-kVp and 80-keV images in FBP (p < 0.05). The subjective score was 4.90±0.298, which was higher than that of other groups (p < 0.05).
Conclusions:
Compared with conventional chest CT images in the arterial phase, 80keV+50% ASIR-V images can effectively eliminate beam-hardening artefacts and improve image quality.
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