Related Experiment Video
Updated: Sep 28, 2025
08:36
The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living
Published on: July 28, 2022
4.0K
A Modified Progressive Supranuclear Palsy Rating Scale for Virtual Assessments.
Anne-Marie Wills1, Alexander Pantelyat2, Alberto Espay3
1Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Summary
Modified Progressive Supranuclear Palsy Rating Scales (PSPRS) assessed remotely show high agreement with the original scale. These teleneurology-friendly versions can predict survival, aiding PSP research and care.
Area of Science:
- Neurology
- Clinical Assessment
- Teleneurology
Background:
- The reliability of the Progressive Supranuclear Palsy Rating Scale (PSPRS) via teleneurology remains unverified.
- Assessing PSP severity and progression remotely is crucial for patient care and research.
Purpose of the Study:
- To evaluate modified PSPRS versions for teleneurology administration.
- To determine if removing specific items impacts the measurement of PSP severity and progression.
Main Methods:
- Secondary analysis of two datasets: Davunetide trial and a single-center cohort.
- Two modified PSPRS versions (mPSPRS-25 and mPSPRS-21) were created by removing specific items.
- Intraclass correlation coefficients (ICC) and proportional hazards models were used for analysis.
Main Results:
- The mPSPRS-25 demonstrated excellent agreement (ICC=0.99) with the original PSPRS at baseline and over 12 months.
- The mPSPRS-21 also showed high agreement (ICC=0.94-0.95) with the original PSPRS.
- Both modified scales effectively predicted survival in the single-center cohort.
Conclusions:
- Modified PSPRS versions are reliable for remote assessment via teleneurology.
- The mPSPRS-21 is particularly suitable for facilitating clinical care and research in Progressive Supranuclear Palsy.
- Remote assessment tools enhance accessibility and efficiency in managing PSP.
