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Published on: November 10, 2023
Clinical Profile and Outcome of COVID-19 Cases Admitted at a Tertiary Health Facility In South-West Nigeria
T O Ojo1, T A Adetunji2, A A Amuda3
1Department of Community Health, Obafemi Awolowo University and Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, Nigeria.
Insights
This study analyzed 65 Nigerian COVID-19 patients, finding male predominance and common symptoms like cough and breathlessness. Most patients recovered, but deaths occurred early in those with severe comorbidities.
Area of Science:
- Infectious Diseases
- Public Health
- Clinical Medicine
Background:
- Coronavirus Disease 2019 (COVID-19) is a significant global health concern.
- Nigeria experienced its third wave of COVID-19, necessitating increased hospitalizations.
- Characterizing clinical profiles and outcomes is crucial for managing novel diseases like COVID-19.
Purpose of the Study:
- To characterize the clinical profile of COVID-19 patients admitted to an isolation center in Nigeria.
- To determine the outcomes of hospitalized COVID-19 patients.
- To identify factors associated with COVID-19 patient outcomes in the Nigerian context.
Main Methods:
- A case series design was employed.
- Data were collected from 65 COVID-19 patients admitted between June 2020 and March 2021.
- Demographic, clinical, treatment, and outcome data were analyzed.
Main Results:
- The majority of patients (72.3%) were under 65 years old, with a male predominance (60.0%).
- Common symptoms included cough (64.6%), breathlessness (63.1%), and fever (61.5%).
- Hypertension (63.1%) and diabetes (27.7%) were the most frequent comorbidities; 66.2% received oxygen therapy, and 89.3% were discharged, with 9.2% mortality.
Conclusions:
- Male patients were more prevalent in the isolation center.
- All recorded COVID-19 mortalities occurred within five days of admission.
- Prompt management of hypoxemia and comorbidities is recommended for favorable COVID-19 outcomes.
Background:
Coronavirus Disease 2019 (COVID-19) is anemerging disease with a global spread that has affected millions of lives. In Nigeria, the third wave of the outbreak is being experienced with many patients requiring hospitalization. Being a novel disease, we characterized the clinical profile and outcomes of patients admitted into our isolation centre.
Methods:
A case series of 65 COVID-19 patients admitted at theIsolation Centre of Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, from June 2020 to March 2021 is presented. Information on demographic characteristics, medical history, symptoms, treatment and outcomes was obtained. Data were analysed using SPSS version 25.
Results:
Most (47; 72.3%) patients were less than 65 years old and 39 (60.0%) were males. The commonest symptoms were cough (42; 64.6%), breathlessness (41; 63.1%), fever (40; 61.5%), muscle aches (40; 61.5%), and anosmia (16; 24.6%). Hypertension (41; 63.1%) and diabetes (18; 27.7%) were the most predominant comorbidities. Forty-three patients (66.2%) had supplemental oxygen therapy. The majority (44; 70%) of patients were admitted for 10 days or less and 58 (89.3%) patients were discharged home. However, 6 deaths (9.2%) were recorded among patients with advanced comorbidities and severe sepsis with all deaths occuring within 5 days of admission.
Conclusion:
There was a male predominance among patients admitted at the Isolation Centre and all mortalities occurred within five days of admission. Early detection, prompt management of cases with hypoxaemia and optimal treatment of comorbidities are recommended for good outcomes in COVID-19 patients.
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