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The mystery of optimal endometrial thickness…never too thick, but when is thin…too thin?

Richard P Buyalos1, Gary D Hubert1, Mousa I Shamonki1

  • 1Fertility and Surgical Associates of California, Thousand Oaks, California; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of California, Los Angeles (UCLA) School of Medicine, Los Angeles, California.

Fertility and Sterility
|April 3, 2022
PubMed
Abstract

No abstract available in PubMed .

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The uterine wall consists of three histological layers: the perimetrium, myometrium, and endometrium. The outermost perimetrium is a thin, serous membrane connected with the broad ligament on the sides, which helps anchor the uterus in the pelvic cavity. The thickest layer, myometrium, is mainly made up of smooth muscle tissue bundles. Its contractions are vital in facilitating the expulsion of the uterine lining, fetus, and placenta during menstruation and childbirth.
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The proliferative phase typically occurs after menstruation and lasts between 6 to 13 days in a standard 28-day cycle. This phase involves the reconstruction of the endometrium, guided by estrogen produced by the developing ovarian follicle.
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