Genomic & structural diversity and functional role of potassium (K⁺) transport proteins in plants

Potassium (K⁺) is an essential macronutrient for plant growth and productivity. It is the most abundant cation in plants and is involved in various cellular processes. Variable K⁺ availability is sensed by plant roots, consequently K⁺ transport proteins are activated to optimize K⁺ uptake. In addition to K⁺ uptake and translocation these proteins are involved in other important physiological processes like transmembrane voltage regulation, polar auxin transport, maintenance of Na⁺/K⁺ ratio and stomata movement during abiotic stress responses. K⁺ transport proteins display tremendous genomic and structural diversity in plants. Their key structural features, such as transmembrane domains, N-terminal domains, C-terminal domains and loops determine their ability of K⁺ uptake and transport and thus, provide functional diversity. Most K⁺ transporters are regulated at transcriptional and post-translational levels. Genetic manipulation of key K⁺ transporters/channels could be a prominent strategy for improving K⁺ utilization efficiency (KUE) in plants. This review discusses the genomic and structural diversity of various K⁺ transport proteins in plants. Also, an update on the function of K⁺ transport proteins and their regulatory mechanism in response to variable K⁺ availability, in improving KUE, biotic and abiotic stresses is provided.