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Updated: Sep 28, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Cemiplimab in cutaneous squamous cell carcinomas (SCC): an overview and a clinical case
Antonio Ghidini1, Domenico Santangelo2, Giovanni Vaccaro2
1Oncology Unit, Ospedale Giovanni Paolo II, Sciacca, AG, Italy.
Introduction:
Cemiplimab, a monoclonal antibody directed against the PD-1 receptor of immune cells, has recent indication for the treatment of patients with locally advanced or metastatic cutaneous squamous cell carcinoma (cSCC).
Case Description:
We present the clinical case of an elderly woman affected by locally advanced squamous carcinoma of the left cheek, in excellent response after only one course of therapy with cemiplimab, with good tolerability.
Conclusions:
Immunotherapy is a new therapeutic option in cSCC.
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