Improving mental, physical, and social functioning through participation in a 3-week cognitive processing therapy-based intensive PTSD treatment
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Updated: Sep 28, 2025

Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure
Published on: January 18, 2021
Dale L Smith1, Merdijana Kovacevic2, Mauricio Montes2
1Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA; Behavioral Sciences, Olivet Nazarene University, Bourbonnais, IL, USA.
Abstract:
Research has supported the utility of brief intensive treatment programs (ITPs) which utilize interventions, such as Cognitive Processing Therapy (CPT), for reducing severity of symptoms among veterans with posttraumatic stress disorder (PTSD). These treatments have produced large overall reductions in PTSD severity and demonstrated the persistence of these gains following treatment. However, the potential effects of ITPs on mental, physical, and social functioning following treatment completion has been largely unexplored. We utilized data from 204 veterans and 5 service members who completed a 3-week CPT-based ITP and 3-month follow-up assessments. We used a two-stage mixed effects location-scale model approach to initially model each participant's amount of PTSD change over time and used these estimates to predict mental, physical, and social functioning three months following treatment. Veterans reported moderate improvements in mental, physical, and social functioning from pre-treatment to 3-month follow-up (ds = 0.52,.42,.55, and.47, respectively). Results indicated that reductions in PTSD severity during treatment, rather than fluctuation in symptom reporting from one assessment to the next, significantly predicted improved mental, physical, and social functioning at follow-up. This study supports the ability of ITPs to enact meaningful improvement in functioning among veterans with PTSD in a short timeframe.
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