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Updated: Sep 28, 2025

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model
Published on: August 5, 2021
Bilateral anterior segment dysgenesis in a 7-week-old domestic shorthaired cat
1Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.
Abstract:
A 7-week-old, intact, female domestic shorthaired cat was presented to the Atlantic Veterinary College (AVC) Ophthalmology service for a 1-week history of buphthalmia in the left eye and bilateral elevated intraocular pressures. Ocular examination revealed bilateral non-visual glaucomatous eyes. Bilateral enucleations were performed without complications and histopathology revealed anterior segment dysgenesis of varying degrees in both eyes. Key clinical message: Anterior segment dysgenesis is a developmental condition that can result in primary congenital glaucoma for which the best course of treatment is enucleation.

