Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...

Endocarditis III: Medical Management

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...

Aortic Regurgitation I: Introduction

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...

Endocarditis I: Introduction

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...

Endocarditis IV: Nursing Management

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Altered blood-brain barrier permeability is associated with abnormal distant connectivity and regional homogeneity in covert hepatic encephalopathy-A cross-sectional study.

Hepatology (Baltimore, Md.)·2025

Same author

Female patient perspective on the incorporation of genital skin examination during routine total body skin exams.

Archives of dermatological research·2024

Same author

Establishing a proactive geriatrician led comprehensive geriatric assessment in older emergency surgery patients: Outcomes of a pilot study.

International journal of clinical practice·2018

Same author

Asymmetric type F botulism with cranial nerve demyelination.

Emerging infectious diseases·2012

Same author

Prevalence of GB virus type C in urban Americans infected with human immunodeficiency virus type 1.

Retrovirology·2005

Search research articles

Related Experiment Video

Updated: Sep 28, 2025

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Gonococcal endocarditis with aortic root abscess and severe aortic insufficiency.

Neelam Tailor¹, Matthew R Dean², Michelle Dellalana³

¹Division of Infectious Diseases, University of Connecticut School of Medicine, Farmington, CT, United States.

|April 4, 2022

Summary

Gonorrhea, a common sexually transmitted infection, can rarely lead to gonococcal endocarditis, a life-threatening heart valve complication. Early diagnosis and surgical intervention are crucial for preventing mortality in affected young adults.

Keywords:

Aortic root abscess Disseminated gonococcal infections Gonococcal endocarditis Neisseria gonorrhoeae Pelvic inflammatory disease

More Related Videos

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Related Experiment Videos

Last Updated: Sep 28, 2025

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Area of Science:

Infectious Diseases
Cardiology
Public Health

Background:

Gonorrhea, caused by *Neisseria gonorrhoeae*, is a prevalent sexually transmitted infection globally, particularly affecting individuals aged 15-24.
While often asymptomatic, gonorrhea can manifest as various conditions, including pelvic inflammatory disease in women and urethritis in men.
Disseminated gonococcal infection (DGI) can lead to systemic complications like arthritis and tenosynovitis.

Observation:

Gonococcal endocarditis is a rare but severe complication of DGI, reported in 1-2% of cases.
This cardiac manifestation characteristically involves the aortic valve, presenting with large vegetations and abscesses.
Few cases have been documented since the introduction of penicillin, underscoring its rarity.

Findings:

The case report emphasizes the critical nature of gonococcal endocarditis as a life-threatening complication.
Aortic valve involvement with significant vegetation and abscess formation is a key pathological feature.
The study highlights the limited reported instances of this condition in medical literature.

Implications:

Timely diagnosis of gonococcal endocarditis is paramount for effective patient management.
Prompt surgical evaluation and intervention are essential to mitigate mortality risks in affected young patients.
This case underscores the need for increased awareness of rare but severe complications of common STIs.