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Updated: Sep 28, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Factors responsible for the emergence of novel viruses: An emphasis on SARS-CoV-2
Sanjeeb Mohapatra1, N Gayathri Menon2
1NUS Environmental Research Institute, National University of Singapore, 1 Create Way, Create Tower, #15-02, 138602, Singapore.
Abstract:
Structural and genetic differences among various viruses play a significant factor in host infectivity and vulnerability to environmental stressors. Zoonoses of viruses require several recombinations and mutations in their genetic material and among several viruses allowing them to switch hosts and infect new species. Additionally, the host genetics play a significant role in successful viral transmission among various hosts. For example, human immunodeficiency virus (HIV), Ebola virus and influenza viruses. In efficient zoonotic events, selective stresses in the host milieu-interieur are critical during viral infection of the first human host. The genetic rearrangement of the virus and the selective environmental pressure of the host immune system dominate the emergence of new viral disease outbreaks.
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