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Updated: Sep 28, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
No correlation between diffuse idiopathic skeletal hyperostosis and coronary artery disease on computed tomography
Christine Dan Lantsman1, Yafim Brodov2, Shlomi Matetzky2
1Department of Diagnostic Imaging, 26744Sheba Medical Center, Tel Hashomer, Israel, affiliated with the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
This study found no independent link between diffuse idiopathic skeletal hyperostosis (DISH) and coronary artery disease (CAD) severity, as measured by CACS and CAD-RADS scores. Findings suggest a complex, potentially non-causal relationship between DISH and CAD.
Area of Science:
- Cardiology
- Radiology
- Rheumatology
Background:
- Previous research suggested an association between diffuse idiopathic skeletal hyperostosis (DISH) and coronary artery disease (CAD).
- The relationship between DISH and objective measures of CAD requires further investigation.
Purpose of the Study:
- To examine the association between DISH and CAD using coronary artery calcification score (CACS) and CAD-Reporting and Data System (CAD-RADS) in patients with chest pain.
- To determine if DISH is an independent predictor of CAD severity.
Main Methods:
- Cardiac CT scans were analyzed for CACS, CAD-RADS, and the presence of DISH.
- Statistical analysis explored the association between DISH and CAD metrics, with and without adjustment for atherosclerotic risk factors.
Main Results:
- Of 268 patients, 24.3% had DISH.
- Univariate analysis showed higher CACS in the DISH group, but this was not significant in multivariate analysis.
- A trend towards higher CAD-RADS scores in the DISH group was observed but did not reach statistical significance after adjustments.
Conclusions:
- No independent association was found between DISH and CACS or CAD-RADS scores.
- The relationship between coronary artery disease and DISH appears complex and potentially non-causal.
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