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Paediatrics: how to manage pediculosis capitis
Alexander K C Leung1,2, Joseph M Lam3, Kin Fon Leong4
1Department of Pediatrics, The University of Calgary, Calgary, Alberta, Canada.
Drugs in Context
|April 4, 2022
Summary
Pediculosis capitis, or head lice, management involves topical treatments like permethrin and pyrethrin. Alternative options and oral medications are available for resistant cases, with safety considerations for young children.
Area of Science:
- Dermatology
- Parasitology
- Public Health
Background:
- Pediculosis capitis is a widespread parasitic infestation primarily affecting children.
- Effective management strategies are crucial to control its spread and impact.
Purpose of the Study:
- To provide an updated narrative review on the current management of pediculosis capitis.
- To synthesize evidence on various treatment options and their efficacy.
Main Methods:
- A comprehensive literature search was conducted on PubMed using keywords such as "pediculosis capitis" and "head lice."
- The review included clinical trials, meta-analyses, and other relevant studies published within the last decade.
- Articles were restricted to those published in English.
Main Results:
- Topical permethrin and pyrethrin are recommended where resistance is low.
- Alternative topical treatments include malathion, benzyl alcohol, dimethicone, spinosad, and ivermectin for resistant cases.
- Oral ivermectin and trimethoprim/sulfamethoxazole are reserved for treatment failures.
Conclusions:
- Multiple topical pediculicides are effective, but safety concerns exist for children under two.
- Pediculicide resistance, particularly to neurotoxic agents, is a significant challenge.
- New treatments require rigorous evaluation for safety and effectiveness; wet combing alone is insufficient.
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