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Published on: June 11, 2020
Myocarditis Secondary to COVID-19 mRNA Vaccine: A Case Report
Lina M Mohammed1, Vikramjeet Dhillon1, Juyong Peter Bong1
1Family Medicine Residency Program, Adventist Health System-Central Valley Network, Hanford, USA.
Abstract:
Vaccine-induced myocarditis has been acknowledged in the past as a rare complication after vaccine administration including influenza and smallpox. Over the past year, there has been an increased number of myopericarditis cases reported by The Center for Disease Control and Prevention (CDC) following the administration of the BNT162b2 and mRNA-1273 vaccines. Most of these cases were among healthy young male adolescents. We report a case of myocarditis in a young male adolescent who presented with chest pain 2 weeks following the first dose of the mRNA COVID-19 vaccine. In the context of the COVID-19 pandemic, we believe it's crucial for healthcare providers to recognize and consider myocarditis as a differential diagnosis in young otherwise healthy individuals who present with chest pain and cardiac symptoms.
Insights
Vaccine-induced myocarditis is a rare complication, with increased reports in young males after mRNA COVID-19 vaccination. Healthcare providers should consider myocarditis in adolescents with chest pain post-vaccination.
Area of Science:
- Cardiology
- Vaccinology
- Public Health
Background:
- Myocarditis is a known rare complication of certain vaccines.
- Recent reports indicate an increase in myopericarditis following mRNA COVID-19 vaccines (BNT162b2 and mRNA-1273).
- This rise in cases is particularly noted among healthy young male adolescents.
Observation:
- This study details a case of myocarditis in a young male adolescent.
- The patient presented with chest pain approximately two weeks after receiving the first dose of an mRNA COVID-19 vaccine.
- The patient was otherwise healthy prior to symptom onset.
Findings:
- The case presentation supports a potential link between mRNA COVID-19 vaccination and the development of myocarditis in adolescents.
- Myocarditis following vaccination requires careful clinical evaluation.
Implications:
- Healthcare providers must consider myocarditis in the differential diagnosis for young males presenting with cardiac symptoms post-vaccination.
- Early recognition and diagnosis are crucial for managing vaccine-associated myocarditis.
- This highlights the importance of ongoing surveillance for vaccine safety and adverse events.

