Related Experiment Video
Updated: Sep 28, 2025
Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
Published on: November 8, 2024
Effect of cervical alignment change after anterior cervical fusion on radiological adjacent segment pathology
Lifeng Li1, Na Li1, Jiahui Zhou2
1Department of Radiology, The Third Xiangya Hospital, Central South University, Changsha, China.
Background:
Adjacent segment pathology (ASP) is one of the primary complications affecting the long-term efficacy of anterior cervical fusion (ACF). At present, the cause and mechanism of adjacent segmental lesions are still controversial.
Methods:
We performed a retrospective analysis on 88 patients with cervical spondylotic myelopathy (CSM) who had been followed up for at least 1 year after ACF. The patients were divided into radiological adjacent segment pathology (RASP) and non-RASP groups according to the presence of postoperative RASP. On the lateral radiographs of the cervical spine of all patients taken before and after surgery at the short-term and final follow-ups, the following parameters were measured: C2-7 Cobb angle of the cervical vertebrae; Cobb angle of the operated segments; and the anterior and posterior height of the fused segments [i.e., the anterior fusion segment height (AFH) and the posterior fusion segment height (PFH)]. The intra- and inter-group differences of the patients before and after surgery were calculated, as well as correlation of ACF with the occurrence of RASP.
Results:
There were 42 cases in the RASP group and 46 cases in the non-RASP group. In the RASP group, the C2-7 Cobb angle was significantly reduced in the short term after surgery (20.42±9.92° vs. 13.81±8.52°, P<0.01), while in non-RASP group the C2-7 Cobb angle was significantly increased in the short term after surgery (12.65±11.91° vs. 15.35±10.05°, P<0.05). The heights of both the anterior and posterior fused segments in the 2 groups were significantly higher after surgery, and they were significantly lower at the final follow-up than at the short-term follow-up. Post-operative AFH change was significantly correlated with C2-7 Cobb angle (r=0.274, P=0.010) and fused segment Cobb angle change (r=0.333, P=0.002). However, Cox regression analysis showed that only the postoperative C2-7 Cobb angle change was associated with RASP, with a hazard ratio of 0.336.
Conclusions:
Decreased cervical lordosis after ACF may be related to postoperative RASP. Maintaining good cervical curvature after surgery may reduce the incidence of RASP after ACF.
