Related Experiment Video
Updated: Sep 28, 2025

Porous Silicon Microparticles for Delivery of siRNA Therapeutics
Published on: January 15, 2015
Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A
Parya Kazemzadeh1, Khalil Sayadi2, Ali Toolabi3
1Department of Chemistry, Lorestan University, Khorramabad, Iran.
Abstract:
Mesoporous silica nanoparticles (MSNs) are widely used as a promising candidate for drug delivery applications due to silica's favorable biocompatibility, thermal stability, and chemical properties. Silica's unique mesoporous structure allows for effective drug loading and controlled release at the target site. In this review, we have discussed various methods of MSNs' mechanism, properties, and its drug delivery applications. As a result, we came to the conclusion that more in vivo biocompatibility studies, toxicity studies, bio-distribution studies and clinical research are essential for MSN advancement.
Related Concept Videos
Factors Affecting Dissolution: Particle Size and Effective Surface Area
Drug Delivery: Overview
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Pore Transport and Ion-Pair Transport
Pore transport, also known as convective transport, is a process where small molecules like urea, water, and sugars rapidly cross cell membranes as though there were channels or pores in the membrane. Although direct microscopic evidence is limited but the concept of pores or channels is widely accepted based on physiological evidence. Despite the lack of direct...
Factors Influencing Drug Absorption: Physicochemical Parameters
Enhanced drug absorption can be achieved by reducing particle sizes and increasing surface areas, thereby facilitating...

