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Related Experiment Video

Updated: Sep 28, 2025

Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
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Diet and acne: A systematic review.

James Meixiong1,2, Cristina Ricco3, Chirag Vasavda1,2

  • 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland.

JAAD International
|April 4, 2022
PubMed
Summary

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High glycemic index diets and increased carbohydrate intake are linked to acne. Dairy intake may also contribute to acne, particularly in Western populations. Further research is needed.

Area of Science:

  • Dermatology
  • Nutrition Science
  • Endocrinology

Background:

  • Acne vulgaris is a prevalent skin condition.
  • Dietary factors, including glycemic load and dairy consumption, influence hormones implicated in acne development.
  • Hormones such as insulin, insulin-like growth factor 1, and androgens play a role in acnegenesis.

Purpose of the Study:

  • To systematically review high-quality evidence on the association between dietary glycemic and dairy intake and acne.
  • To synthesize current research on the impact of diet on acnegenesis.

Main Methods:

  • A comprehensive literature search of MEDLINE was conducted for English-language papers.
  • The search covered studies examining the association between diet and acne without timeline restrictions.
Keywords:
GI, glycemic indexIGF-1, insulin-like growth factor 1LOE, level of evidenceRCT, randomized control trialacnedairydietglycemic indexrandomized control trialsugar

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  • Evidence quality was assessed using the Ottawa quality assessment scale.
  • Main Results:

    • 34 articles met inclusion criteria from 410 initially identified.
    • High glycemic index and glycemic load intake showed a positive association with acnegenesis and severity.
    • The association between dairy intake and acne was mixed, potentially influenced by sex, ethnicity, and dietary habits.

    Conclusions:

    • High glycemic index, glycemic load, and carbohydrate intake have a modest but significant proacnegenic effect.
    • Increased dairy consumption may be proacnegenic in specific populations, especially those with Western dietary patterns.
    • The influence of diet on acne is likely sex- and ethnicity-dependent, necessitating further randomized trials.