Model-Based Recommendations for Optimal Surgical Placement of Epiretinal Implants
Michael Beyeler1,2,3, Geoffrey M Boynton1, Ione Fine1,2
1Department of Psychology, University of Washington, Seattle, WA 98195, USA.
Summary
Optimizing electronic retinal implant placement can significantly reduce visual "streaks" by up to 55%. This study recommends ideal electrode array positioning for improved visual perception in retinal implant users.
Area of Science:
- Biomedical Engineering
- Neuroscience
- Ophthalmology
Background:
- Current electronic retinal implants stimulate both target retinal ganglion cells and passing axons, causing visual "streaks" that degrade image quality.
- The shape of perceived visuals is influenced by the stimulating electrode's retinal location, but this is not yet used in surgical planning.
Purpose of the Study:
- To explore optimal electrode array configurations for retinal implants.
- To provide recommendations for improved intraocular positioning of retinal implants to enhance visual perception.
Main Methods:
- Utilized a psychophysically validated computational model to simulate various implant configurations.
- Systematically explored the parameter space of electrode array positioning within the retina.
Main Results:
- Demonstrated that optimized implant placement can reduce axonal activation spatial extent by up to approximately 55%.
- Identified an optimal implant location, feasible for surgery and stable across individuals, based on simulated patient data.
Conclusions:
- Computer-aided simulations can guide patient-specific planning for retinal implant surgery.
- Improved electrode placement is a viable strategy to enhance the visual experience for individuals with retinal implants.


