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International consensus statement on allergy and rhinology: Olfaction.
Zara M Patel1, Eric H Holbrook2, Justin H Turner3
1Otolaryngology, Stanford University School of Medicine, Stanford, California, USA.
International Forum of Allergy & Rhinology
|April 4, 2022
Summary
This consensus document consolidates global expertise on clinical olfaction, addressing olfactory loss and dysfunction. It critically reviews evidence to guide diagnosis and treatment, identifying knowledge gaps for future research.
Area of Science:
- Otolaryngology
- Neuroscience
- Allergy Research
Background:
- Rapid expansion of literature on clinical olfaction, olfactory loss, and dysfunction.
- Significant variability in the quality of existing research necessitates critical review.
- Need for a consolidated, evidence-based resource on olfaction.
Purpose of the Study:
- To produce an International Consensus on Allergy and Rhinology: Olfaction (ICAR:O) document.
- To critically review and consolidate the rapidly expanding body of literature on olfaction.
- To provide expert consensus on diagnosis, treatment, and research in olfactory dysfunction.
Main Methods:
- Development of specific topics related to olfaction by experts.
- Assignment of literature reviews, evidence-based reviews, or evidence-based reviews with recommendations.
- Iterative review and integration of topics by global authors for final consensus.
Main Results:
- The ICAR:O document covers nearly 100 topics in clinical olfaction.
- Topics include diagnosis, epidemiology, disease burden, testing, etiology, treatment, and associated pathologies.
- Comprehensive review of current evidence and expert opinion on olfaction.
Conclusions:
- Provides critical insight and clarity on evaluating, diagnosing, and treating olfactory dysfunction.
- Highlights existing gaps in knowledge and the evidence base for olfactory disorders.
- Guides future research directions in the field of clinical olfaction.
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