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Updated: Sep 28, 2025

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
Current Role of Allogeneic Stem Cell Transplantation in Multiple Myeloma
Jean-Sébastien Claveau1, Francis K Buadi1, Shaji Kumar2
1Division of Hematology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Abstract:
Major progress in the treatment of multiple myeloma has been made in the last several years. However, myeloma remains incurable and patients with high-risk cytogenetics or advanced stage disease have an even worsen survival. Only allogeneic transplantation may have curative potential in some patients. However, the high non-relapse mortality and incidence of chronic graft-versus-host disease have raised controversy regarding this procedure. In this review, we will address the role of upfront and delayed allogeneic transplant.
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