New potential of boron-based COFs: the biocompatible COF-1 for reactive oxygen generation and antimicrobial
Yiying Zhang1, Xiaoqing Xu2, Qiaobo Liao1
1School of Chemistry and Chemical Engineering, Nanjing University, Jiangsu 210023, China. xikai@nju.edu.cn.
Abstract:
Photocatalytic covalent organic frameworks (COFs) are popular in the field of biomedical materials and also have potential as antimicrobial materials. Herein, a boron-based COF was used in antibacterial applications innovatively. The results of this study suggested that COF-1, the earliest boroxine COF, could produce a variety of reactive oxygen species (ROS) under visible light irradiation. In order to explore more applications of COF-1, antibacterial tests were carried out based on the above results. The test results showed that the material displayed an obvious bactericidal effect on Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) by releasing ROS under white light. According to the results of plate coating, all bacteria died after co-cultivation with COF-1 under white light for about 120 minutes. In a word, this study could provide a new idea for the application of boron-based COFs as multifunctional photocatalysts in future.
Related Concept Videos
Hydroboration-Oxidation of Alkenes
Properties of Organometallic Compounds
Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation
One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
Oxidation and Reduction of Organic Molecules
The removal of an electron from a molecule, results in a...
Exceptions to the Octet Rule
MO Theory and Covalent Bonding


