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Updated: Jun 23, 2026

Techniques for Processing Eyes Implanted With a Retinal Prosthesis for Localized Histopathological Analysis
Published on: August 2, 2013
An infrared image-enhancement algorithm in simulated prosthetic vision: Enlarging working environment of future
Junling Liang1, Heng Li1, Jianpin Chen1
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Background:
Most existing retinal prostheses contain a built-in visible-light camera module that captures images of the surrounding environment. Thus, in case of insufficient or lack of visible light, the camera fails to work, and the retinal prostheses enter a dormant or "OFF" state. A simple and effective solution is replacing the visible-light camera with a dual-mode camera. The present research aimed to achieve two main purposes: (1) to explore whether the dual-mode camera in prosthesis recipients works under no visible-light conditions and (2) to assess its performance.
Methods:
To accomplish these aims, we enrolled subjects in a psychophysical experiment under simulated prosthetic vision conditions. We found that the subjects could complete some simple visual tasks, but the recognition performance under the infrared mode was significantly inferior to that under the visible-light mode. These results inspired us to develop and propose a feasible infrared image-enhancement processing algorithm. Another psychophysical experiment was performed to verify the feasibility of the algorithm.
Results:
The obtained results showed that the average efficiency of the subjects completing visual tasks using our enhancement algorithm (0.014 ± 0.001) was significantly higher (p < 0.001) than that of subjects using direct pixelization (0.007 ± 0.001).
Conclusions:
We concluded that a dual-mode camera could be a feasible solution to improving the performance of retinal prostheses as the camera adapted better to the specific existing ambient light conditions. Dual-mode cameras combined with this infrared image-enhancement algorithm could provide a promising direction for the design of future retinal prostheses.
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