Related Experiment Video
Updated: Sep 28, 2025

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
In severe COVID-19, high-flow vs. conventional oxygen therapy reduced intubation and time to clinical recovery at 28
Christopher R Carpenter1, Peter A D Steel2
1Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA (C.R.C.).
Source Citation:
Ospina-Tascón GA, Calderón-Tapia LE, García AF, et al. Effect of high-flow oxygen therapy vs conventional oxygen therapy on invasive mechanical ventilation and clinical recovery in patients with severe COVID-19: a randomized clinical trial. JAMA. 2021;326:2161-71. 34874419.
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