Five Years Follow-Up of Acrysof Cachet® Angle-Supported Phakic Intraocular Lens Implantation for Myopia Correction

Area of Science:

• Ophthalmology
• Refractive Surgery
• Ophthalmic Lenses

Background:

• High refractive errors pose challenges for vision correction.
• Phakic intraocular lenses (pIOLs) offer a surgical option for correcting significant refractive errors.
• The AcrySof Cachet® angle-supported pIOL is designed for this purpose.

Purpose of the Study:

• To evaluate the long-term efficacy and safety of the AcrySof Cachet® angle-supported pIOL.
• To assess visual acuity outcomes over a 60-month follow-up period.
• To monitor endothelial cell density and other safety parameters post-implantation.

Main Methods:

• Retrospective analysis of consecutive clinical cases.
• Comprehensive ophthalmologic examinations pre- and post-implantation.
• Inclusion of objective and subjective refraction, visual acuity, endothelial cell density, and imaging techniques.

Main Results:

• Significant improvements in uncorrected (UCVA) and corrected distance visual acuity (CDVA) were observed.
• Mean UCVA improved from 1.33 logMAR pre-surgery to 0.20 logMAR at five years.
• Mean CDVA improved from 0.10 logMAR pre-surgery to 0.04 logMAR at five years.
• Endothelial cell loss averaged 11.51% at one year and 15.95% at five years.
• No intraoperative complications were reported.

Conclusions:

• The AcrySof Cachet® angle-supported pIOL demonstrates favorable efficacy and safety outcomes up to five years.
• Positive impacts on visual acuity (UCVA, CDVA) and endothelial cell density (ECD) were noted.
• Potential for significant endothelial cell loss necessitates regular patient follow-up.