Related Experiment Video
Updated: Sep 28, 2025

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
A Case of Heart Transplantation for Fulminant Myocarditis After ChAdOx1 nCoV-19 Vaccination
Seok Hyun Kim1, Soo Yong Lee2, Ga Yun Kim1
1Division of Cardiology, Department of Internal Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
Abstract:
Vaccines have become the mainstay of management against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019; COVID-19) in the absence of effective antiviral therapy. Various adverse effects of COVID-19 vaccination have been reported, including cardiovascular complications such as myocarditis or pericarditis. Herein, we describe clinical records of a 63-year woman with fulminant myocarditis following ChAdOx1 nCoV-19 vaccination that was salvaged by heart transplantation. She complained chest pain, nausea, vomiting, and fever after the second vaccination. After the heart transplantation, the patient died due to necrotizing pneumonia on the 54th day of onset. Fulminant myocarditis is very rare after ChAdOx1 nCoV-19 vaccination but can be fatal.
Related Concept Videos
Myocarditis III: Medical Management
Myocarditis IV: Nursing Management
Cardiomyopathy V: Interprofessional Care
Myocarditis I: Introduction
Cardiomyopathy II: Dilated Cardiomyopathy
Pericarditis III: Medical Management

