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Rectifying nematode names.

Jonathan Hodgkin1

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The nematode worm Caenorhabditis elegans is a key model organism. This article details the history and development of its widely accepted gene naming and genetic nomenclature system.

Area of Science:

  • * Developmental Biology
  • * Genetics
  • * Molecular Biology

Background:

  • * Caenorhabditis elegans (C. elegans) has been a prominent model organism for 50 years.
  • * Its utility spans genetics, developmental biology, and neuroscience.
  • * Standardized nomenclature is crucial for clear scientific communication.

Purpose of the Study:

  • * To trace the historical development of gene naming conventions in C. elegans.
  • * To outline the origins of the established genetic nomenclature system.
  • * To provide context for current C. elegans research practices.

Main Methods:

  • * Historical literature review.
  • * Analysis of key publications and community standards.
  • * Chronological documentation of nomenclature evolution.
Keywords:
Caenorhabditis elegansdatabasegene mappinggene namesgenetic nomenclaturenematodestock center

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  • * Demonstration of a consistent and evolving system over five decades.

Conclusions:

  • * The C. elegans nomenclature system is a product of community consensus and scientific progress.
  • * Understanding its history aids in interpreting past and present research.
  • * The established system facilitates robust genetic and molecular studies in C. elegans.