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Related Concept Videos

Vitamins01:30

Vitamins

1.0K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Disorders of Erythrocytes01:27

Disorders of Erythrocytes

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Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
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Deindividuation00:57

Deindividuation

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Deindividuation is a form of social influence on an individual’s behavior such that the individual engages in unusual or non-normal behavior while in a group setting. Why? Because in these group settings, the individual no longer sees themselves as an individual anymore, disinhibiting their behavior and personal restraint.
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Epistaxis01:30

Epistaxis

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Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Clinical Profile and Neurological Outcomes of Pediatric Patients Supported on Venoarterial Extracorporeal Mechanical Oxygenation in a Cardiorespiratory Pediatric Intensive Care Unit: A Single-Center Study.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2025
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Updated: Sep 28, 2025

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

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Scurvy in Children: The Silent Masquerader.

Swathy Subhash1, Sanuja Titus Santosh1

  • 1Department of Paediatrics, KIMSHEALTH, Trivandrum, Kerala, India.

Journal of Tropical Pediatrics
|April 5, 2022
PubMed
Summary

Scurvy, a vitamin C deficiency, can mimic various illnesses and is often overlooked by clinicians. Prompt diagnosis and vitamin C supplementation led to a full recovery in a school-aged boy presenting with leg pain.

Area of Science:

  • Nutritional Science
  • Pediatrics
  • Clinical Medicine

Background:

  • Scurvy is historically recognized but rarely diagnosed in modern clinical practice.
  • Classic scurvy symptoms include bleeding gums, but it can present with diverse, non-specific signs.
  • The rarity of scurvy contributes to a lack of awareness among healthcare professionals, leading to diagnostic challenges.

Purpose of the Study:

  • To highlight the diagnostic challenges of scurvy in contemporary medicine.
  • To present a case study of a child with atypical scurvy presentation.
  • To emphasize the importance of considering scurvy in differential diagnoses for unexplained symptoms.

Main Methods:

  • Case report of a school-aged boy with lower limb pain and gait disturbance.
Keywords:
nutritionscurvyvitamin C

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  • Clinical evaluation by multiple specialists prior to pediatric diagnosis.
  • Radiographic assessment for bone changes and serum ascorbic acid level determination.
  • Main Results:

    • The patient exhibited X-ray findings characteristic of scurvy.
    • Low serum ascorbic acid levels confirmed vitamin C deficiency.
    • Symptomatic improvement and complete recovery were observed following vitamin C supplementation.

    Conclusions:

    • Scurvy can present with varied symptoms, mimicking other conditions and challenging clinicians.
    • Early recognition and appropriate vitamin C therapy are crucial for favorable outcomes in scurvy.
    • This case underscores the need for heightened clinical suspicion for scurvy in pediatric patients with unexplained musculoskeletal complaints.