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Updated: Sep 28, 2025

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
Incisional metastatic breast carcinoma deposit in a total knee replacement presenting as peri-prosthetic joint
Aysha Rajeev1, Ahmed Elzawahry1, Simren Rakhra1
1Queen Elizabeth Hospital, Gateshead Health Foundation NHS Trust, Sheriff Hill, Gateshead NE9 6SX, UK.
Abstract:
Cutaneous metastasis from the primary breast carcinoma occurs when the disease is wide spread and can present as skin infection especially in a previous well-healed scar. If the secondary deposit is over a total knee incisional site it can mimic peri-prosthetic joint infection. We report a rare and unusual case of a woman who presented with clinical signs and symptoms of a peri-prosthetic total knee replacement which on biopsy turned out to be cutaneous metastasis from a previously treated breast cancer. Chronic granulation tissue in a total joint incisional scar may present as peri-prosthetic joint infection. A good history taking and clinical examination with specimens from the skin lesions send for both microbiology and histopathology is recommended to arrive at an early and accurate diagnosis.
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