RADx Tech Viability and Steering Panels: A Model for MedTech Translational Grant Review

Area of Science:

• Biomedical Engineering
• Public Health
• Diagnostic Test Development

Background:

• The RADx Tech program aimed to accelerate SARS-CoV-2 test deployment, bypassing lengthy traditional grant processes.
• Typical grant application and review cycles can take 4 to 6 months, hindering rapid response.
• Leveraged established methodologies from CIMIT and POCTRN for a streamlined approach.

Purpose of the Study:

• To describe the RADx Tech program's innovative multi-stage review process for rapid diagnostic test deployment.
• To highlight the effectiveness of the "assess, improve, and then select" methodology.
• To demonstrate the potential extensibility of this review model beyond the RADx Tech program.

Main Methods:

• Implemented a multi-stage review system involving a Viability Panel and a Steering Panel.
• Supported panels with subject matter experts and a dedicated Deep Dive team.
• Utilized an "assess, improve, and then select" process with experienced reviewers.

Main Results:

• The Viability Panel assessed proposal fit and recommended progression to a Deep Dive.
• The Steering Panel reviewed Deep Dive outcomes to decide on further funding.
• Consistent review across all applications by both panels ensured context and reliability.

Conclusions:

• The RADx Tech review process significantly improved timing, efficiency, and effectiveness.
• The "assess, improve, and then select" model, with experienced panels, is a successful strategy.
• This approach demonstrates potential for broader application in accelerating technology deployment.