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Updated: Sep 28, 2025

Development of a Novel Task-oriented Rehabilitation Program using a Bimanual Exoskeleton Robotic Hand
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Randomized feasibility trial of the Scleroderma Patient-centered Intervention Network hand exercise program

Marie-Eve Carrier1, Linda Kwakkenbos1,2, Isabelle Boutron3,4

  • 1Lady Davis Institute of the Jewish General Hospital, Montreal, Quebec - Canada.

Journal of Scleroderma and Related Disorders
|April 6, 2022
PubMed
Summary

Systemic sclerosis (SSc) patients can now access an online hand exercise program (SPIN-HAND) to improve hand function. A feasibility trial will assess its suitability for a larger study, ensuring robust methodology for future rehabilitation interventions.

Keywords:
Feasibility studiesSclerodermaSystemicTele-rehabilitationTrial protocols

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Area of Science:

  • Rehabilitation medicine
  • Rheumatology
  • Digital health interventions

Background:

  • Systemic sclerosis (SSc) frequently causes significant hand dysfunction.
  • Developing effective hand rehabilitation interventions for SSc patients presents challenges.
  • The Scleroderma Patient-centered Intervention Network (SPIN) developed the online SPIN-HAND program to address this need.

Purpose of the Study:

  • To evaluate the feasibility of conducting a full-scale randomized controlled trial (RCT) for the SPIN-HAND online hand exercise program.
  • To assess trial implementation processes, resource requirements, management, scientific validity, and participant engagement.
  • To inform necessary adjustments for a future large-scale RCT.

Main Methods:

  • A feasibility trial conducted within the SPIN Cohort using a cohort multiple RCT design.
  • Randomization of 40 English-speaking SSc participants with hand limitations (Cochin Hand Function Scale ≥3) to either the SPIN-HAND program or usual care for 3 months.
  • Focus on evaluating trial feasibility aspects including acceptability and usage.

Main Results:

  • The feasibility trial is designed to assess the practicality and effectiveness of the SPIN-HAND program's implementation.
  • Key outcomes will include data on trial processes, resource needs, scientific rigor, and participant adherence.
  • Results will guide modifications prior to a full-scale RCT.

Conclusions:

  • The SPIN-HAND feasibility trial aims to ensure a robust and participant-centered methodology for a future full-scale RCT.
  • Successful implementation of this trial will provide crucial data for optimizing the SPIN-HAND program.
  • This work is essential for advancing hand function rehabilitation in SSc patients.