[Mononuclear phagocytes, the hemostasis system and the intravascular coagulation syndrome]

The author analyses the reported data and his own findings concerned with the involvement of mononuclear phagocytes in the regulation of hemostasis and in the pathogenesis of a number of frequently occurring forms of the hemostatic system pathology. The content of monocytic thromboplastin was measured in 56 patients with the intravascular blood coagulation syndrome of varying etiology. Production of monocytic thromboplastin reached the highest degree in patients with purulent conditions whereas in patients presenting with the terminal stage of sepsis, it did not exceed normal or even dropped down, which may be connected with depletion of monocytes because of their preliminary hyperactivation.