Unusual Mandibular Distraction Complication in Two Neonatal Pierre Robin Sequence Patients

Area of Science:

• Craniofacial Surgery
• Pediatric Otolaryngology
• Genetics and Rare Diseases

Background:

• Pierre Robin sequence (PRS) involves micrognathia, glossoptosis, and airway obstruction.
• Conservative management and surgical interventions like mandibular distraction are used for PRS.
• Severe airway obstruction in PRS necessitates prompt intervention.

Purpose of the Study:

• To report two cases of sublingual salivary gland hypertrophy in PRS patients.
• To investigate the implications of this hypertrophy in the context of mandibular distraction surgery.
• To highlight a potential complication associated with PRS airway management.

Main Methods:

• Case report of two patients diagnosed with Pierre Robin sequence.
• Review of clinical presentation and management strategies.
• Analysis of sublingual salivary gland hypertrophy in relation to mandibular distraction.

Main Results:

• Two PRS patients presented with severe airway obstruction requiring intervention.
• Sublingual salivary gland hypertrophy was identified as a complicating factor.
• Mandibular distraction was performed in both cases, with specific considerations for the hypertrophy.

Conclusions:

• Sublingual salivary gland hypertrophy can occur in Pierre Robin sequence patients with severe airway obstruction.
• This hypertrophy may present challenges during mandibular distraction surgery.
• Further investigation into the management of this specific complication is warranted.