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Updated: Sep 27, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

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Genetic and non-genetic risk factors associated with atrial fibrillation

Lindsay J Young1, Steve Antwi-Boasiako1, Joel Ferrall2

  • 1The Frick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, USA.

Life Sciences
|April 6, 2022
PubMed

Insights

Atrial fibrillation (AF), a common heart rhythm disorder, affects millions and increases stroke risk. This review explores AF causes, genetic and environmental factors, and links to COVID-19, aiding prevention and treatment.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Genetics

Background:

  • Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia.
  • AF prevalence is rising, particularly with age, increasing stroke risk.
  • Understanding AF pathogenesis is crucial for effective management.

Purpose of the Study:

  • To review cellular and tissue pathways involved in AF.
  • To identify genetic and environmental risk factors for AF.
  • To explore the relationship between SARS-CoV-2 infection and AF.

Main Methods:

  • Literature review of existing studies on AF.
  • Analysis of genetic and environmental influences on AF susceptibility.
  • Examination of molecular and cellular mechanisms in AF.

Main Results:

  • AF pathogenesis involves complex tissue and cellular pathways.
  • Genetic predisposition and environmental factors significantly impact AF risk.
  • Emerging evidence suggests a potential link between SARS-CoV-2 and AF.

Conclusions:

  • Elucidating AF mechanisms is key for developing preventative strategies.
  • Early diagnostics and targeted therapies can improve AF patient outcomes.
  • Further research into SARS-CoV-2 and AF is warranted.

Keywords:
Atrial fibrillationCOVID-19EnvironmentGeneticsPreventative care

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