Polyphenol-based hydrogels: Pyramid evolution from crosslinked structures to biomedical applications and the reverse
Zimu Li1, Zhidong Chen1, Hongzhong Chen1
1Institute of Pharmaceutics, School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China.
Bioactive Materials
|April 7, 2022
Summary
Polyphenol-based hydrogels, derived from nature, offer unique adhesion, toughness, and self-healing properties for diverse biomedical uses. This review details their design, properties, and applications, paving the way for future innovations.
Area of Science:
- Materials Science
- Biomedical Engineering
- Polymer Chemistry
Background:
- Polyphenol-based hydrogels are nature-derived bioactive materials with remarkable properties like adhesion, toughness, and self-healing.
- Their unique crosslinking structures underpin these properties, leading to broad biomedical applications.
Purpose of the Study:
- To classify common polyphenol-based hydrogels.
- To elaborate on the structure-property-application relationships of these hydrogels.
- To propose reverse design strategies and discuss future prospects.
Main Methods:
- Literature review and analysis of polyphenol-based hydrogel systems.
- Classification based on crosslinking structures.
- Discussion of property evolution and biomedical applications.
Main Results:
- Detailed classification of polyphenol-based hydrogels.
- Elucidation of the link between crosslinking structure, material properties, and biomedical utility.
- Proposal of reverse design considerations for optimized hydrogel systems.
Conclusions:
- Polyphenol-based hydrogels present significant potential in various biomedical fields.
- Further research and innovative design are crucial for overcoming existing challenges and unlocking future applications.
